Genomic Risk Analysis
Your DNA knows how to keep you alive longer
Your DNA already contains early warning signals for hundreds of conditions. We turn your existing DNA file into 2,800+ polygenic risk scores, 1,636 protein predictions, and a personalized longevity protocol — so you can act before symptoms ever appear.
Two rounds of beta testing complete. Validated by bioinformaticians and physicians.
A user uploaded their DNA data. With no prior medical history provided, Helix flagged duodenal ulcer risk at the 97th percentile and digestive system cancer risk at the 99.9th percentile.
That user had already been diagnosed with stage 3 oesophageal cancer. The genome saw it. No symptoms were needed. No medical records were provided. Just raw DNA.
If that analysis had been run five years earlier, proactive screening could have caught it at stage 1 — when the survival rate is over 90%.
Your DNA doesn’t change. The sooner you read it, the more time you have to act on it.
15 AI agents. 18 databases. 1,636 proteins. One report.
Deep imputation, Bayesian-weighted risk scoring, protein PRS prediction, convergence signal detection, and clinical narrative synthesis. Every step visible.
DNA Upload
Beagle 5.5
PRS Engine
Unified DBProtein PRSDrop your 23andMe, Ancestry, or MyHeritage file. 10 seconds.
Beagle 5.5 expands ~700K variants to 28M+ via 1000 Genomes & TOPMed.
3,550 PGS risk models + 1,636 protein PRS + ClinVar/gnomAD annotation.
Parallel AI collectors query 18 databases via MCP using Bayesian weighted lookups.
Narrative synthesis: protocols, summaries, doctor’s report, supplement & training plans.
Report by email. DNA permanently deleted.
Privacy policy →18 Databases Our Agents Access via MCP
Click any database to visit the official source
Polygenic risk models
VisitPathogenic variants
VisitAssociation studies
VisitPharmacogenomics guidelines
VisitDrug-gene annotations
VisitAI pathogenicity
VisitDeleteriousness scores
VisitAllele frequencies
VisitGene-disease validity
VisitDisease-gene links
VisitMendelian diseases
VisitCancer variants
VisitGenotype summaries
VisitPhenotype ontology
VisitRare diseases
VisitImputation panel
VisitWGS reference
VisitPrediction models
VisitInteractive reports & downloadable PDFs
Genomic Health Report
2,800+ risk scores across every major disease category. 1,636 protein PRS predictions. Pharmacogenomics for 200+ medications. ClinVar pathogenic variant scanning. AI-generated longevity protocol with supplements, training, and diet.
Explore Demo ReportGenetically-informed longevity protocol with personalized supplement stack, training plan, and dietary guidance.
Example PDFComplete polygenic risk score analysis across 2,800+ conditions with percentiles and confidence levels.
Example PDFComprehensive genomic analysis including risk scores, pathogenic variants, and clinical protocols.
Example PDFCYP enzyme status, affected medications, and CPIC dosing recommendations for your physician.
Example PDFCompare your DNA with anyone who matters
Upload two DNA files and watch every variant light up. Trace what you inherited from each parent. Discover shared risk factors with your partner. Screen for carrier conditions before starting a family. The full version is fully interactive — hover any variant to explore it.
Every shared & unique variant between two genomes
Trace Inheritance
See exactly which alleles came from which parent. Every variant traced to its origin with confidence scoring.
Family Planning
Both carry a CFTR variant? Both carry sickle cell trait? Reproductive carrier screening flags recessive conditions before they matter.
Fun Traits
Bitter taste, cilantro preference, caffeine metabolism, earwax type, asparagus smell — see which parent gave you what.
Rare Disease Research
For families investigating inherited conditions. Compare across generations to trace how rare variants segregate.
Live comparison of two real genomes with full inheritance tracing
Not another “you have blue eyes” report
Polygenic Risk Scores
Cardiovascular, neurological, metabolic, autoimmune, and cancer. The same PGS Catalog models used in research hospitals.
ClinVar Variant Scanning
Every variant checked against ClinVar’s pathogenic database. Drug interactions, carrier status, and pharmacogenomics.
Longevity Protocol
Supplements, training, and diet matched to your DNA. Cross-referenced against your actual risk scores.
DNA deleted after analysis. SHA-256 deletion certificate as cryptographic proof. Nothing remains.
Feed It To Your AI
Export your full genetic profile to ChatGPT, Claude, or any AI via MCP. Your DNA becomes permanent context for health advice.
Data You Already Own
Millions have unused DNA data from 23andMe, Ancestry, or MyHeritage. No new test — upload what you have.
What people are saying
“I got my reports and they are very impressive and accurate based on my experience and history. They are much more insightful than many of the DNA analysis reports I have paid for from other sites. Good work.”
“Wonderful reports. My wife is a physician who lectures on AI in medicine and would also like to evaluate the service. Can you send me a second invite?”
“I’m a bioinformatician, I do stuff like this on the regular. The parts you’ve given details about make me think it’s a legit tool. I’d like to talk to you about the nuts and bolts further.”
“I work as a bioinformatician for a lab where we also develop risk scores. I also use Beagle 5.5 for imputation; it is by far the best one.”
“My results and my mother’s are consistent. Also, there definitely is a history of heart disease in the family.”
“Ran it. It gave accurate one. My family history diseases etc etc.”
Backed by peer-reviewed science
Top 5th percentile PRS for coronary heart disease = 2–3 fold higher risk, comparable to monogenic mutations.
PRS outperformed smoking, diabetes, hypertension, BMI, cholesterol, and family history for predicting CHD.
MI-GENES trial: PRS-integrated risk assessments led to lower LDL and fewer cardiovascular events over 10 years.
PRSs for heart disease, diabetes, Alzheimer’s, breast cancer, and prostate cancer used clinically worldwide.
Source: Kullo, I.J. “Clinical use of polygenic risk scores.” Nature Reviews Genetics (2025).
Get a DNA chip test
Order a consumer DNA kit, download your raw data file, and upload it here for full analysis.
Ready to decode your genome?
The information in your DNA could change the course of your health. Upload your existing file and find out what your genome has been trying to tell you.
Everything you need to know
We accept raw data exports from 23andMe (all versions), AncestryDNA, MyHeritage, LivingDNA, and FamilyTreeDNA. Files can be .txt, .csv, .tsv, .zip, or .gz format. Most consumer DNA chips contain 600K–900K variants.
Every score uses peer-reviewed, published models from the PGS Catalog — the same database used by research hospitals. Each score shows its confidence level and the number of variants used. With deep imputation enabled, coverage jumps from ~30% to ~95%, making scores significantly more powerful. PRS show relative genetic risk compared to the population.
Your DNA file is deleted immediately after analysis completes. All intermediate files are purged within 2 hours. You receive a SHA-256 Data Deletion Certificate proving destruction. We do not store, sell, or share your genetic data.
2,800+ polygenic risk scores across cardiovascular, cancer, metabolic, neurological, and autoimmune categories. ClinVar pathogenic variant scanning. Pharmacogenomics (drug response) analysis. A personalized longevity protocol with actionable recommendations. All delivered as an interactive HTML report.