Question 1

What DNA files do you accept?

Accepted Answer

We accept raw data exports from 23andMe (all versions), AncestryDNA, MyHeritage, LivingDNA, and FamilyTreeDNA. Files can be .txt, .csv, .tsv, .zip, or .gz format. Most consumer DNA chips contain 600K–900K variants.

Question 2

How accurate are polygenic risk scores?

Accepted Answer

Every score uses peer-reviewed PGS Catalog models selected for report-grade coverage and relevance. Each score shows percentile direction and coverage. With imputation enabled, coverage jumps from ~30% to ~95%, making scores significantly more useful. PRS show relative genetic tendency compared to the population.

Question 3

What happens to my DNA data after analysis?

Accepted Answer

Your DNA file is deleted immediately after analysis completes. All intermediate files are purged within 2 hours. You receive a SHA-256 Data Deletion Certificate proving destruction. We do not store, sell, or share your genetic data.

Question 4

What’s included in the report?

Accepted Answer

300+ carefully curated polygenic risk scores across cardiovascular, cancer, metabolic, neurological, immune, and trait categories, surfaced after coverage and quality filtering. ClinVar variant scanning, pharmacogenomics, protein pathway context, training and diet guidance, and downloadable evidence packs are delivered as an interactive HTML report.

Question 5

What is imputation?

Accepted Answer

Consumer DNA chips only test ~700K positions out of your 3 billion base pairs. Imputation uses a reference panel to infer additional positions that were not directly measured. This improves polygenic risk score coverage, especially when key model variants are not present on the original chip.

Question 6

How long does analysis take?

Accepted Answer

Without imputation: 2–5 minutes. With imputation enabled: 15–45 minutes depending on server load. You’ll receive your report by email when it’s ready.

Question 7

Is this a medical diagnostic tool?

Accepted Answer

No. Helix Sequencing is for research and educational purposes. Results should be discussed with a healthcare provider before making medical decisions. Polygenic risk scores show relative genetic predisposition, not diagnoses.

Question 8

Can I compare my DNA with a family member?

Accepted Answer

Yes. Our DNA Compare feature lets you trace variant inheritance between two related individuals — see which alleles came from which parent, identify shared risk factors, and explore inherited traits side by side.

Demo genomic health report

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