Genomic Risk Analysis
Evidence-backed genomic intelligence from the DNA data you already own
Turn an existing DNA file into curated PRS, protein pathway context, pharmacogenomics, variant evidence, and structured AI reports for prevention-focused review. Genetic signals are not diagnoses; they help decide what may be worth investigating earlier.
Beta-tested across 50+ reports. Clinical and privacy review ongoing.
One frontier AI agent. 18 databases. 300+ curated PRS scores. One report.
Imputation, coverage-filtered risk scoring, protein PRS prediction, pharmacogenomics, and evidence-backed report synthesis. Every step visible.
Drop your 23andMe, Ancestry, or MyHeritage file. 10 seconds.
Optional imputation improves PRS model coverage using reference panels.
Surface 300+ curated report scores, protein PRS, variant context, and PGx from the filtered evidence layer.
One frontier model reasons over the evidence pack and writes structured report JSON.
Signals, technical evidence, medication safety, diet, training, PDFs, and JSON export.
Report by email. DNA permanently deleted.
Privacy policy →18 Databases Queried by the Evidence Layer
Click any database to visit the official source
Curated report PRS
VisitPathogenic variants
VisitAssociation studies
VisitPharmacogenomics guidelines
VisitGene-drug guidance pairs
VisitAI pathogenicity
VisitDeleteriousness scores
VisitAllele frequencies
VisitGene-disease validity
VisitDisease-gene links
VisitMendelian diseases
VisitCancer variants
VisitGenotype summaries
VisitPhenotype ontology
VisitRare diseases
VisitImputation panel
VisitWGS reference
VisitPrediction models
VisitInteractive reports & downloadable PDFs
Genomic Health Report
300+ carefully curated risk scores surfaced after coverage and quality filtering. High-quality protein pathway signals, pharmacogenomics for 200+ medications, variant context, and a prevention-focused plan with training and diet.
Explore Demo ReportClinician-readable summary generated from the same demo report data, including medication-safety context.
Example PDFCurated polygenic risk score analysis across 300+ high-coverage traits with percentiles and evidence context.
Example PDFComprehensive genomic analysis including risk scores, candidate variants, protein context, and report rationale.
Example PDFCompact source evidence behind the demo report, formatted so you can pass it to your own AI tools.
Example JSONCompare your DNA with anyone who matters
Upload two DNA files and watch every variant light up. Trace what you inherited from each parent. Discover shared risk factors with your partner. Screen for carrier conditions before starting a family. The full version is fully interactive — hover any variant to explore it.
Every shared & unique variant between two genomes
Trace Inheritance
See exactly which alleles came from which parent. Every variant traced to its origin with confidence scoring.
Family Planning
Both carry a CFTR variant? Both carry sickle cell trait? Reproductive carrier screening flags recessive conditions before they matter.
Fun Traits
Bitter taste, cilantro preference, caffeine metabolism, earwax type, asparagus smell — see which parent gave you what.
Rare Disease Research
For families investigating inherited conditions. Compare across generations to trace how rare variants segregate.
Live comparison of two real genomes with full inheritance tracing
Not another “you have blue eyes” report
Curated PRS Scores
Carefully filtered cardiovascular, neurological, metabolic, immune, cancer, and trait scores with report-grade coverage.
ClinVar Variant Scanning
Every variant checked against ClinVar’s pathogenic database. Drug interactions, carrier status, and pharmacogenomics.
Prevention Focus
Training and diet guidance matched to the report evidence, with clear separation between genetic signals and clinical decisions.
DNA deleted after analysis. SHA-256 deletion certificate as cryptographic proof. Nothing remains.
Feed It To Your AI
Export your full genetic profile to ChatGPT, Claude, or any AI via MCP. Your DNA becomes permanent context for health advice.
Data You Already Own
Millions have unused DNA data from 23andMe, Ancestry, or MyHeritage. No new test — upload what you have.
What people are saying
“I got my reports and they are very impressive and accurate based on my experience and history. They are much more insightful than many of the DNA analysis reports I have paid for from other sites. Good work.”
“Wonderful reports. My wife is a physician who lectures on AI in medicine and would also like to evaluate the service. Can you send me a second invite?”
“I’m a bioinformatician, I do stuff like this on the regular. The parts you’ve given details about make me think it’s a legit tool. I’d like to talk to you about the nuts and bolts further.”
“I work as a bioinformatician for a lab where we also develop risk scores. I also use Beagle 5.5 for imputation; it is by far the best one.”
“My results and my mother’s are consistent. Also, there definitely is a history of heart disease in the family.”
“Ran it. It gave accurate one. My family history diseases etc etc.”
Backed by peer-reviewed science
Top 5th percentile PRS for coronary heart disease = 2–3 fold higher risk, comparable to monogenic mutations.
In selected studies and clinical contexts, PRS can add risk-stratification value alongside smoking, diabetes, blood pressure, BMI, cholesterol, and family history.
MI-GENES follow-up suggests PRS-informed risk review can support earlier LDL-lowering action in appropriate cardiovascular contexts.
Health systems and research programs are evaluating PRS for heart disease, diabetes, Alzheimer’s, breast cancer, and prostate cancer.
Source: Kullo, I.J. “Clinical use of polygenic risk scores.” Nature Reviews Genetics (2025).
Get a DNA chip test
Order a consumer DNA kit, download your raw data file, and upload it here for full analysis.
Ready to decode your genome?
Helix is currently running as an invite-only beta while privacy and clinical review continue. Approved users can upload an existing DNA file and receive the full report bundle.
Everything you need to know
We accept raw data exports from 23andMe (all versions), AncestryDNA, MyHeritage, LivingDNA, and FamilyTreeDNA. Files can be .txt, .csv, .tsv, .zip, or .gz format. Most consumer DNA chips contain 600K–900K variants.
Every score uses peer-reviewed PGS Catalog models selected for report-grade coverage and relevance. Each score shows percentile direction and coverage. With imputation enabled, coverage jumps from ~30% to ~95%, making scores significantly more useful. PRS show relative genetic tendency compared to the population.
Your DNA file is deleted immediately after analysis completes. All intermediate files are purged within 2 hours. You receive a SHA-256 Data Deletion Certificate proving destruction. We do not store, sell, or share your genetic data.
300+ carefully curated polygenic risk scores across cardiovascular, cancer, metabolic, neurological, immune, and trait categories. Each report surfaces the subset that passes coverage and quality filters, alongside ClinVar variant scanning, pharmacogenomics, protein pathway context, training and diet guidance, and downloadable evidence packs.